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Michael Habeck

Address: Spemannstr. 38
72076 Tübingen
Room number: 224
Phone: +49 7071 601 451
Fax: +49 7071 601 552
E-Mail: michael.habeck
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Michael Habeck

Position: Research Group Leader  Unit: 

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Articles (43):

Habeck M Person (2012) Bayesian estimation of free energies from equilibrium simulations Physical Review Letters 109(10) 5 pages.
Paramasivam N , Habeck M Person and Linke D (2012) Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not BMC Genomics 13(1).
Kalev I , Mechelke M , Kopec K , Holder T , Carstens S and Habeck M Person (2012) CSB: A Python framework for computational structural biology Bioinformatics .
Honndorf VS , Coudevylle N , Laufer S , Becker S , Griesinger C and Habeck M Person (2012) Inferential NMR/X-ray-Based Structure Determination of a Dibenzo[a,d]cycloheptenone Inhibitor–p38a MAP Kinase Complex in Solution Angewandte Chemie 51(10) 2359-2362.
Paulmann M , Arnold T , Linke D , Özdirekcan S , Kopp A , Gutsmann T , Kalbacher H , Wanke I , Schuenemann V , Habeck M Person, Buerck J , Ulrich AS and Schittek B (2012) Structure-activity analysis of the dermi-cidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat Journal of Biological Chemistry 287(11) 8434-8443.
Shahid S , Bardiaux B , Franks T , Krabben L , Habeck M Person, Rossum B and Linke D (2012) Membrane protein structure by solid-state NMR: insights into the autotransport mechanism of YadA Nature Methods . accepted
Mechelke M and Habeck M Person (2012) A probabilistic model for secondary structure prediction from protein chemical shifts Proteins . submitted
Habeck M Person (2012) Bayesian flexible fitting of biomolecular structures into EM maps Biophysical journal . submitted
Mechelke M and Habeck M Person (2012) Calibration of Boltzmann distribution priors in Bayesian data analysis Physical Review E . submitted
Kalev I Person and Habeck M Person (2011) HHfrag: HMM-based fragment detection using HHpred Bioinformatics 27(22) 3110-3116.
Hirsch M Person, Schölkopf B Person and Habeck M Person (2011) A Blind Deconvolution Approach for Improving the Resolution of Cryo-EM Density Maps Journal of Computational Biology 18(3) 335-346.
Habeck M Person and Nilges M (2011) Combining computational modeling with sparse and low-resolution data Journal of Structural Biology 173(3) 419.
Habeck M Person (2011) Statistical mechanics analysis of sparse data Journal of Structural Biology 173(3) 541-548.
Armache J-P , Jarasch A , Anger AM , Villa E , Becker T , Bhushan S , Jossinet F , Habeck M Person, Dindar G , Franckenberg S , Marquez V , Mielke T , Thomm M , Berninghausen O , Beatrix B , Söding J , Westhof E , Wilson DN and Beckmann R (2010) Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution Proceedings of the National Academy of Sciences of the United States of America 107(46) 19748-19753.
Armache J-P , Jarasch A , Anger AM , Villa E , Becker T , Bhushan S , Jossinet F , Habeck M Person, Dindar G , Franckenberg S , Marquez V , Mielke T , Thomm M , Berninghausen O , Beatrix B , Söding J , Westhof E , Wilson DN and Beckmann R (2010) Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome Proceedings of the National Academy of Sciences of the United States of America 107(46) 19754-19759.
Mechelke M and Habeck M Person (2010) Robust probabilistic superposition and comparison of protein structures BMC Bioinformatics 11(363) 1-13.
Habeck M Person (2009) Generation of three-dimensional random rotations in fitting and matching problems Computational Statistics 24(4) 719-731.
Djuranovic S , Hartmann MD , Habeck M Person, Ursinus A , Zwickl P , Martin J , Lupas AN and Zeth K (2009) Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal ATPases Molecular Cell 34(5) 580-590.
Bardiaux B , Bernard A , Rieping W , Habeck M Person, Malliavin TE and Nilges M (2009) Influence of Different Assignment Conditions on the Determination of Symmetric Homo-dimeric Structures with ARIA Proteins 75(3) 569-585.
Alva VS , Dunin-Horkawicz S , Habeck M Person, Coles M and Lupas AN (2009) The GD box: A widespread non-contiguous supersecondary structural element Protein Science 18(9) 1961–1966.
Hirsch M Person and Habeck M Person (2008) Mixture Models for Protein Structure Ensembles Bioinformatics 24(19) 2184-2192.
Bayrhuber M , Meins T , Habeck M Person, Becker S , Giller K , Villinger S , Vonrhein C , Griesinger C , Zweckstetter M and Zeth K (2008) Structure of the human voltage-dependent anion channel Proceedings of the National Academy of Sciences of the United States of America 105(40) 15370-15375.
Nilges M , Bernard A , Bardiaux B , Malliavin T , Habeck M Person and Rieping W (2008) Accurate NMR Structures Through Minimization of an Extended Hybrid Energy Structure 16(9) 1305-1312.
Bardiaux B , Bernard A , Rieping W , Habeck M Person, Malliavin T and Nilges M (2008) Graphical Analysis of NMR Structural Quality and Interactive Contact Map of NOE Assignments in ARIA BMC Structural Biology 8(30) 1-5.
Habeck M Person, Nilges M and Rieping W (2008) A Unifying Probabilistic Framework for Analyzing Residual Dipolar Couplings Journal of Biomolecular NMR 40(2) 135-144.
Wolff N , Izadi-Pruneyre N , Scholes J , Habeck M Person, Linge J , Rieping W , Wandersman C , Nilges M , Delepierre M and Lecroisey A (2008) Comparative Analysis of Structural and Dynamic Properties of the Loaded and Unloaded Hemophore HasA: Functional Implications Journal of Molecular Biology 376(2) 517-525.
Rieping W , Nilges M and Habeck M Person (2008) ISD: A Software Package for Bayesian NMR Structure Calculation Bioinformatics 24(8) 1104-1105.
Nilges M , Habeck M Person and Rieping W (2008) Probabilistic Structure Calculation Comptes Rendus Chimie 11(4-5) 356-369.
Habeck M Person (2007) Bayesian Reconstruction of the Density of States Physical Review Letters 98(20, 200601) 1-4.
Rieping W , Habeck M Person, Bardiaux B , Bernard A , Malliavin TE and Nilges M (2007) ARIA2: automated NOE assignment and data integration in NMR structure calculation Bioinformatics 23(3) 381-382.
Nicastro G , Habeck M Person, Masino L , Svergun DI and Pastore A (2006) Structure validation of the Josephin domain of ataxin-3: Conclusive evidence for an open conformation Journal of Biomolecular NMR 36(4) 267-277.
AB E , Atkinson A , Banci L , Bertini I , Ciofi-Baffoni S , Brunner K , Diercks T , Dotsch V , Engelke F , Folkers GE , Griesinger C , Gronwald W , Gunther U , Habeck M Person, de Jong RN , Kalbitzer HR , Kieffer B , Leeflang BR , Loss S , Luchinat C and Marquardsen T (2006) NMR in the SPINE Structural Proteomics project Acta Crystallographica D: Biological Crystallography 62(10) 1150-1161.
Nilges M , Habeck M Person, Zdravković Si and Rieping W (2006) Error distribution derived NOE distance restraints Proteins 64(3) 652-664.
Habeck M Person, Rieping W and Nilges M (2006) Weighting of experimental evidence in macromolecular structure determination Proceedings of the National Academy of Sciences of the United States of America 103(6) 1756-1761.
Rieping W , Habeck M Person and Nilges M (2005) Modeling Errors in NOE Data with a Log-normal Distribution Improves the Quality of NMR Structures J. Am. Chem. Soc. 127 16026-16027.
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Habeck M Person, Rieping W and Nilges M (2005) Bayesian estimation of Karplus parameters and torsion angles from three-bond scalar couplings constants Journal of Magnetic Resonance 177(1) 160-165.
Habeck M Person, Nilges M and Rieping W (2005) Bayesian inference applied to macromolecular structure determination Physical Review E 72(3,1) 031912-031912.
Rieping W , Habeck M Person and Nilges M (2005) Inferential structure determination. Science 309 303.
Habeck M Person, Nilges M and Rieping W (2005) Replica-exchange Monte Carlo scheme for bayesian data analysis. Phys Rev Lett. 94 018105-018105.
Linge JP , Habeck M Person, Rieping W and Nilges M (2004) Correction of spin diffusion during iterative automated NOE assignment. J Magn Reson. 167 334.
Linge JP , Habeck M Person, Rieping W and Nilges M (2004) ARIA: automated NOE assignment and NMR structure calculation. Bioinformatics 19 315.
Fogh R , Ionides J , Ulrich E , Boucher W , Vranken W , Linge JP , Habeck M Person, Rieping W , Bhat TN , Westbrook J , Hendrik K , Gilliland G , Berman H , Thornton J , Nilges M , Markley J and Laue E (2002) The CCPN project: an interim report on a data model for the NMR community. Nat Struct Biol. 9 416.
Muhle-Goll C , Habeck M Person, Carzola O , Nilges M , Labeit S and Granzier H (2001) Structural and functional studies of titin‘s fn3 modules reveal conserved surface patterns and binding to myosin S1--a possible role in the Frank-Starling mechanism of the heart. J Mol Biol. 313 431.

Conference papers (9):

Hirsch M Person, Hofmann M Person, Mantlik F Person, Pichler BJ , Schölkopf B Person and Habeck M Person (2012) A Blind Deconvolution Approach for Pseudo CT Prediction from MR Image Pairs 19th IEEE International Conference on Image Processing (ICIP 2012), IEEE, 2953 -2956.
Habeck M Person (2012) Evaluation of marginal likelihoods via the density of states In: Proceedings of the Fifteenth International Conference on Artificial Intelligence and Statistics (AISTATS 2012), (Ed) N Lawrence and M Girolami, AISTATS 2012, JMLR: W&CP 22, 22, 486--494.
Joubert P Person, Nickell S , Beck F , Habeck M Person, Hirsch M Person and Schölkopf B Person (2011) Automatic particle picking using diffusion filtering and random forest classification International Workshop on Microscopic Image Analysis with Application in Biology (MIAAB 2011), 6 pages.
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Langovoy M Person, Habeck M Person and Schölkopf B Person (2011) Adaptive nonparametric detection in cryo-electron microscopy 58th World Statistics Congress of the International Statistical Institute (ISI 2011), 6 pages.
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Langovoy M Person, Habeck M Person and Schölkopf B Person (2011) Spatial statistics, image analysis and percolation theory 2011 Joint Statistical Meetings (JSM), American Statistical Association, Alexandria, VA, USA, 11 pages.
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Hirsch M Person, Schölkopf B Person and Habeck M Person (2010) A New Algorithm for Improving the Resolution of Cryo-EM Density Maps In: Research in Computational Molecular Biology, Lecture Notes in Bioinformatics, Vol. 6044, (Ed) B Berger, 14th International Conference on Research in Computational Molecular Biology (RECOMB 2010), Springer, Berlin, Germany, 174-188.
Habeck M Person, Rieping W and Nilges M (2004) Estimation of proton configurations from NOESY spectra 24th International Workshop on Bayesian Inference and Maximum Entropy Methods in Science and Engineering, American Institute of Physics, Melville, New York, 119-126.
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